Investigation on Chemical Changes Occur During Purification (Shodhana) of Bhallataka by HPTLC

Ayurveda is a highly progressed and organized system of life and health science based on its own unique original concepts and fundamental principle. Bhallataka is one of the most powerful and fast acting Ayurvedic herb. Bhallataka mentioned under the list of Poisonous substances. Ayurveda advocates Ballataka after shodhana. Bhallataka must be purified before administrating to patients.There are different purification methods (Shodhana) mentioned in Ayurveda, The change that takes place during the Shodhana process can be explored by modern analytical methods. Among the modern Analytical tools HPTLC is a powerful analytical method.9, 11Shodhana process certainly makes changes in the chemical composition of the Bhallataka, So that the toxic and allergic components either eliminated or their quantitative presence is redused. Bhallataka extract (Before and after purification) subjected to HPTLC study for measuring its quantitative presence in all the extracts, it reveals that after purification quantitatively it has been lost from extract. The results stated here certainly indicate the variation of chemical profile of Bhallataka.