Regorafenib Induced Toxic Erythema of Chemotherapy Presenting as Malignant Intertigo with Hand Foot Skin Reaction

Newer chemotherapeutic drugs often present with adverse reactions involving the skin. These reactions may be mistaken for infections, drug allergies or GVHD. Regorafenib is a multikinase inhibitor with a characteristic adverse event profile affecting the hands and feet as well as flexures. Because of a very high incidence of these reactions, adequate precautions to prevent, as well as early diagnosis and management, improve quality of life as well as outcomes of treatment.