Psoriasis: The Immune System Disease with Unknown Etiology Treated with Local Bath PUVA

Psoriasis is a chronic and lifetime disease which relates to the immune system, having unknown etiology. It typically emerges with dermal disorders and sometimes with joint disorders. Psoriasis Palmoplantar is a kind of localized chronic dermatosis in palms of hands and soles of feet; the significance of which is its resistance to treatment and high rate of reoccurrence. Psoriasis Palmoplantar significantly influences the quality of patients' lives due to affecting their everyday life tasks. Procedure: This is a descriptive analytical study, performed in retrospective method. The target society for this study includes all patients suffering from Psoriasis Palmoplantar, who referred to X-Ray Clinic of Razi Hospital during the years of 2005 to 2009 and went under treatment using Local Bath PUVA. Questionnaires were made subject to the data recorded in medical files of patients. Results: Medical files of 95 patients, suffering from Psoriasis Palmoplantar, were investigated in this study. The patients, who referred, went under treatment using Local Bath PUVA at Razi Hospital. 49.5% of the patients were male and 50.5% were female. Average age of patients was 44.17 years. The youngest patient was 6 years old and the oldest was 81 years old. Most of patients were in 4th and 6th decades in age. Average number of treatment sessions for the studied patients were 42.5 sessions and average collective radiation dose was J/CM2 251.8. Occurrence rate of side effects in studied patients was 20%. In final assessment, 16.8% of patients had a very good response to treatments (75% to 100% recovery of disordered dermal surfaces). 35.8% of patients had a good response to treatments (50% to 75%) and 29.5% of patients had an average response to treatments (25% to 50%) and 9.5% of patients had a weak response to treatments (less than 25%) and 8.4% of patients showed complete failure in treatments. In statistical terms, collective radiation dose for patients with very good treatment response (more than 75%) was significantly higher than other patients. The number of treatment sessions in these individuals was significantly higher than other patients. But among those patients with lack of recovery, low recovery and average and good recovery, there was no significant difference in number of sessions or dose of radiation. There was no significant difference between the gender of the patients and their response to the treatment (P: .043). Average age of patients with good recovery response was significantly higher than those with no recovery response (P: .018).