Relationship of Serum C - Reactive Protein with Indices of Metabolic Syndrome among Type 2 Diabetic Pakistani Subjects

Back ground: Metabolic syndrome is risk factor for diabetes and inflammation is the characteristic of metabolic syndrome. The C-reactive protein (CRP) is highly conserved and preferred marker of inflammation. Objective: This cross sectional study was conducted on newly diagnosed type 2 diabetic patients to evaluate the status of CRP with potential risk factors of diabetes including glycemic levels, obesity and lipid profile on their first visit to Amin Hayat Memorial Hospital Lahore. Methods: In this study a total of 100 subjects with age range 40-65 years were included. The subjects were stratified into 4 categories underweight, normal weight, overweight and obese subjects according to Asian standards. Different demographic parameters age, gender, BMI, waist circumference, WHR, B.P, personal history, socioeconomic status were recorded. Serum CRP level was assessed by ELISA technique. Lipid profile was assessed by Hitachi chemical analyzer. Results: It was concluded from the present study that serum CRP level (mg/L) and triglyceride level (mg/dl) were significantly higher among newly diagnosed type-2 diabetic subjects and CRP was significantly associated with indices of metabolic syndrome (BMI, Lipid profile) and random glucose level (<0.05) among diabetic subjects.