Antimicrobial Activity of Methanol, n-Hexane and Dichloromethane Extract of Portulaca oleracea

Portulaca oleracea (Family: Portulacaceae). The antimicrobial activity was performed by disc diffusion method by determining the zone of inhibition of living microorganisms. The methanolic extract showed significant to mild antimicrobial activity than n-hexane and dichloromethane in compared with the standard drug Amoxicillin. The present study we used gram-positive (Klebsiella pneumoniae and Staphylococcus aureus) and gram-negative bacteria (Escherichia coli; Shigella boydii and Pseudomonas aeruginosa). The present results support the use of this plant in the treatment of diseases like abscesses, bilious conditions, and coughs in traditional medicine and also suggest the possibility of isolating antibacterial agents from P. oleracea.