A CASE OF RECURRENT DEMYELINATION

Pediatric multiple sclerosis (MS) is a rare chronic demyelinating disorder involving the central nervous system, spinal cord and optic nerve. Multiple sclerosis in children is characterized by a slightly higher preponderance in males versus females and an onset after 6 years of age. Beyond 12 years of age, the male female ratio becomes 1 2. The disease process mainly targets normally formed white matter through an immune mediated mechanism. It is diagnosed when two de-myelinating episodes localize to distinct CNS regions and when the duration of each episode is greater than 24 hours and each episode is separated by an interval of greater than 30 days. High doses of methyl prednisolone are used to treat relapses. Disease modifying agents are used to reduce the frequency of relapses