Virilizing ovarian Leydig cell tumour
Journal: Journal of Clinical and Scientific Research (Vol.2, No. 2)Publication Date: 2013-04-01
Authors : K.V. Murali Mohan; V. Shanthi; B.A. Rama Krishna; P. Niroopama; M. Anitha;
Page : 101-104
Keywords : Leydig cell tumour; Reinke's crystalloids;
Abstract
Leydig cell tumours belong to the small group of ovarian steroid tumors, which are hormone producing and derived from specific stromal cells. Morphologically, their endocrine-like structure is characteristic, formed of large, polyhedral cells resembling luteal, adrenocortical and Leydig cells. They contain crystalloids of Reinke in their cytoplasm which have diagnostic significance. Patients with these tumours present with androgenic manifestations. We report the occurrence of Leydig cell tumour in a 35-year-old lady who presented with infertility and hirsutism.
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