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AQUA MEDIATED NOVEL, ONE-POT, CATALYST-FREE AND ECONOMICALLY EFFICIENT SYNTHESIS OF FUNCTIONALIZED 2-AMINOTHIAZOLES

Journal: International Journal of Applied and Natural Sciences (IJANS) (Vol.3, No. 3)

Publication Date:

Authors : ; ; ; ; ;

Page : 87-94

Keywords : 2-Aminothiazoles; Environmental Benign Synthesis; Water;

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Abstract

A fast, economically and environment-friendly one-pot method has been developed for the synthesis of 2-aminothiazoles in water without using any catalyst or hazardous co-organic solvent. The products were produced in excellent isolated yields and crude products do not require any further purification. This simple methodology gave an access to a wide range of 2-aminothiazoles and can be employed for the synthesis of many pharmaceutical precursors.

Last modified: 2014-05-23 18:15:22