STUDY OF NEUROPROTECTIVE ACTIVITY OF METHANOLIC EXTRACT OF OXALIS CORNICULATA LINN ON ANIMAL MODELS OF DEPRESSION

Depression and anxiety disorders are the most common mental illnesses, each affecting in excess of 10-15% of the population at some time in their lives. Approximately 450 million people suffer from a mental or behavioural disorder according to the WHO report, resulting in 12.3% of the global burden of disease. Though various therapeutic regimens are used to treat anxiety and depressive disorders; but due to their side effects and dependence liability their use in clinical practice is limited. Research studies on different medicinal plants in various animal models has widely contributed in the search of new therapeutic products for the treatment of various neurological disorders. Hence the present study was undertaken to evaluate the neuroprotective activity of Methanolic extract of Oxalis corniculata Linn on animal models of depression.