TRANSARTERIAL CHEMOEMBOLISATION IN THE TREATMENT OF PATIENTS WITH METASTATIC COLORECTAL CANCER
Journal: I.P. Pavlov Russian Medical Biological Herald (Vol.26, No. 2)Publication Date: 2018-06-30
Authors : A.V. Shabunin M.M. Tavobilov O.V. Paklina D.N. Grekov G.R. Setdikova P.A. Drozdov;
Page : 245-257
Keywords : metastases of colorectal liver cancer; regional chemotherapy; therapeutic pathomorphosis;
Abstract
Aim. To assess effectiveness of chemoembolization of hepatic artery (CEHA) in treatment of patients with metastatic colorectal cancer, and also to determine the optimal interval in combination of CEHA with other treatment methods. Materials and methods. The study includes analysis of the results of treatment of 30 patients with resectable metastases of colorectal cancer in the liver. The first group included 15 patients with resection made 1 week after CEHA. The second group consisted of 15 patients in whom resection operation was made 2 weeks after CENA with subsequent assessment of morphological changes in metastases. Results. Therapeutic pathomorphism was recorded in 25/30 patients. In the first group, therapeutic pathomorphism was observed in 13/15 patients. In 11/13 patients, the 2nd degree of therapeutic pathomorphism was recorded. In 2/13 patients – the 1st degree. In the second group, therapeutic pathomorphism was observed in 12/15 patients. In all patients the 2nd degree of therapeutic pathomorphism was recorded. No significant differences in the degree of therapeutic pathomorphism were recorded on the 7th and 14th day after regional chemotherapy (p=0.436). Conclusion. Hepatic artery chemoembolization is an effective method of treating patients with metastases of colorectal cancer in the liver. In use of chemoembolization of hepatic artery in combination with other surgical methods, the seven-day time interval is optimal.
Other Latest Articles
- Performance and Emission Characteristics of Methyl Ester Mango Seed Biodiesel on Four Stroke Single Sylinder Diesel Engine with 200 bar Injection Pressure
- AGERELATED DYNAMICS OF ELASTICITY OF DEEP DORSAL VEIN OF HUMAN PENIS ACCORDING TO RESULTS OF DIRECT MEASUREMENTS
- Internet Traffic Classification Based on Constrained Based Clustering Technique and Genetic Algorithm
- Single Axis Solar Panel Protection System
- Automatic Solid Waste Removal from Water to Prevent the Contamination, Pollution and Waterborne Diseases
Last modified: 2019-01-09 16:09:56