Comparative Study of Bupivacaine vs Bupivacaine and Ketamine (Intrathecally) During Intraoperative and Post Operative Analgesia in Non PIH Caesarian Section

Obstetric anesthesia is demanding but gratifying subspeciality of anesthesiologist. Anesthetic care of pregnant patient is unique in that two patients are cared for simultaneously; the parturient and the foetus. This study was conducted on 50 parturient of ASA I and ASA II, planed for caesarean section. They were randomly divided into two groups of 25 patients each: Group-A (control) 1.8cc bupivacaine 0.5% + 0.5 cc normal saline. Total 2.3cc and Group-B (study) 1.8cc bupivacaine 0.5% +25 mg ketamine 0.5 cc (preservative free) Total 2.3 cc. We summarized that intrathecal 0.5% bupivacaine with preservative free intrathecal ketamine have rapid onset of sensory block, have better hemodynamic stability and have post operative analgesia without affecting neonate. Thus it is safe modality for the parturient undergoing caesarean section, but central side effects like delirium, nystagmus and sedation can occur in some patients.