PROBIOTIC PROPERTIES OF BACTERIA OF LACTOBACILLUS GENUS ISOLATED FROM THE GASTROINTESTINAL TRACT OF RABBITS

The probiotic properties (antagonistic and adhesion) of lactic acid bacteria isolated from the gastrointestinal tract of rabbits were studied. It was established that the studied antagonistic activity to pathogenic and conditionally pathogenic microorga­nisms was observed in the following strains: Lactobacillus lactis 4/1, Lactobacillus casei 5/4, Lactobacillus helveticus 13/2, Lactobacillus plantarum 17/2, Lactobacillus plantarum 17/3, Lactobacillus acidophilus 49/1. The level of adhesion of lactic acid bacteria isolate, isolated from the gastrointestinal tract of rabbits, to erythrocytes of rabbit, mouse, pig, cattle, human blood was studied. The highest level of adhesion (83 %) was observed in erythrocytes of rabbits, low (53 %) – in erythrocytes of cattle. The possibi­lity of using the L. helveticus 13/2 strain for the prevention and treatment of salmonella infections has been shown. Introduction to research animals of lactic acid bacteria before infection with pathogens of salmonellosis allowed to save 90–100 % of experimental animals. With the use of lactic acid bacteria after infection of salmonellosis to animals, the safety of the herd was 67–73 %.