DISTRIBUTION OF ABO AND RH (D) ALLELE FREQUENCY AMONG ASTHMATIC PATIENTS

The present study was undertaken to investigate the association of ABO and Rh (D) allele frequency with asthma. A total of 180 subjects (120 asthmatics and 60 controls) were analyzed for ABO and Rh (D) blood typing. Blood group O (42.5%) was found to be more frequent in asthmatics as compared to controls (15%). Allele frequency of O was highest in asthmatics (0.652) followed by B (0.247) and A (0.101). Chi- square value for ABO blood group was significant (p0.05) in controls. In both asthmatics as well as healthy subjects Rh (D)+ phenotype was more abundant (87.5% and 88.33% respectively) than Rh (D)- phenotype. D allele was more frequent in both the groups (0.647 in asthmatics and 0.658 in controls).