Effect of Occupational Exposure on Allergic Diseases and Relationship with Serum IgE Levels in the Tannery Workers in Bangladesh
Journal: Bioresearch Communications (BRC) (Vol.02, No. 01)Publication Date: 2016-01-02
Authors : M. Aktar Hossain; Laila N. Islam;
Page : 158-163
Keywords : Tannery workers; allergic diseases; serum IgE; Hazaribagh; Bangladesh.Tannery workers; allergic diseases; serum IgE; Hazaribagh; Bangladesh.;
Abstract
He tannery workers in Hazaribagh, Dhaka, have been found to suffer from a wide range of allergic diseases. Serum IgE level plays a crucial role in the development of allergy. Occupational exposure to chromium compounds and other chemicals used in mineral tanning processes may elevate IgE levels and cause allergy. We evaluated serum IgE levels and investigated its relationship with allergic diseases in the tannery workers and control subjects. The tannery workers had a single or more than one type of allergic diseases including food allergy, allergic contact dermatitis, allergic rhinitis, eosinophilia, allergic urticaria, drug allergy, and non-specific allergy. IgE levels were significantly higher in the tannery workers (339.6 IU/mL) compared to that in the unexposed controls (207.5 IU/mL). Tannery workers without allergic diseases had significantly elevated levels of IgE (313.5 IU/mL) compared to the controls (90.4 IU/mL) without allergy. IgE levels were maximally elevated in the tanners with allergic urticaria (563.4 IU/mL) followed by non-specific allergy (390.1 IU/mL), and food allergy (346.3 IU/mL) whereas control subjects with eosinophilia had maximally elevated levels of IgE (737.1 IU/mL) followed by allergic contact dermatitis (479.1 IU/mL), and allergic urticaria (373.3 IU/mL). Allergy attacks were more frequent in the tanners during the hot season while the control subjects had frequent attacks during the cold season. These observations suggested that occupational exposure to chromium and other toxic chemicals and pollution in the working environment were associated with the development of allergic diseases and elevated levels of IgE in the tannery workers in Bangladesh.
Other Latest Articles
- Identification and expression profiling of microRNAs and their corresponding targets related to phytoremediation of heavy metals in jute (Corchorus olitorius var. O-9897)
- Phylogenetic analysis of Bangladeshi population with reference to D1S80 VNTR locus
- Cloning, characterization and analysis of the Arabidopsis RD29A promoter for its inducible expression in rice under salinity and drought stress
- Nodule inhabiting non-rhizobial bacteria and their influence on growth of selected leguminous plants of Bangladesh
- Mouse homologues of hepatitis C virus human entry factors inhibit the entry of HCV pseudo-particles (HCVpp) into human hepatoma cells
Last modified: 2018-08-13 15:50:49