Cataractostatic Activity of Drynaria quercifolia Tuber Extract
Journal: Bioresearch Communications (BRC) (Vol.03, No. 02)Publication Date: 2017-06-01
Authors : Miraj Kobad Chowdhury Jakir Hossain M Aftab Uddin;
Page : 411-414
Keywords : Cataractostatic activity; Drynaria quercifolia; goat lens; in vitro.;
Abstract
The cataractostatic activity of methanolic and ethylacetate extracts of Drynaria quercifolia tuber were evaluated here as a prospective treatment for lens cataracts. Glucose-induced cataract formed in isolated goat lenses in vitro was used as a model in this investigation. When tested with extracts, it was observed that the ethylacetate extracts of the tuber was able to inhibit cataractogenesis when the lenses were treated at a final concentration of 20 ïg/ml. However, methanolic extract of the tuber showed a moderate anticataract activity at 80 ïg/ml concentration. When justified quantitatively, the cataract formation was inhibited 51.61±9.68% by methanolic extract at 80 ïg/ml. On the contrary, the ethylacetate extract could inhibit cataract formation by 62.37±15.24% at 20 ïg/ml and 100.00±3.23% at 80 ïg/ml. These data indicated that, the ethylacetate extract of Drynaria quercifolia tuber is a potent cataractostatic agent and may be able to prevent diabetic cataract.
Other Latest Articles
- Effect of Different Sawdust Substrates on the Growth, Yield and Proximate Composition of White Oyster Mushroom (Pleurotus ostreatus)
- Evaluation of Antioxidant Activity of Four Locally Grown Aromatic Herbs Commonly Consumed in Bangladesh
- Bangladesh to Benefit from TRIPS Waiver: An Academic Perspective
- Strategic Exploitation of Heme Acquisition by Gram-positive Bacteria from Human Host
- Assessment of Heavy Metal Contents in Surface Sediment of the Tungguk River Surrounding the Industrial Complex of Gebeng City
Last modified: 2018-08-13 16:47:14