Pattern of fixed drug eruptions in a tertiary care teaching hospital Hi-tech medical college, Bhubaneswar, Odisha

Fixed drug eruption (FDE) is one of the common types of cutaneous adverse drug reaction. This study was conducted to study the common types of drugs causing FDE and to find the management pattern of FDE in a tertiary care teaching hospital. In this study we found that orindazole (24%) and co-trimoxazole (20%) had higher incidence of FDE. Sixty eight percent of patients developed post inflammatory pigmentation. The most common clinical presentations was black patch in 44%, followed by bulla with erythematous patch in 20% of pigmented patches. Topical steroids, antihistaminic and oral corticosteroids were the common drugs used in the management of fixed drugs eruptions. The most common affected site was lip in 33.3% followed by trunk in 21%. The most common age group was 11-20 year followed by 21-30 year, fifty-one cases were seen in male.