CLINICAL PROFILE, ANGIOGRAPHIC FINDINGS AND OUTCOMES FOLLOWING INTERVENTION IN PATIENTS WITH TAKAYASU?S ARTERITIS

Objective: To analyse the clinical presentation, angiographic findings and outcome following intervention (endovascular and open surgical) in patients with Takayasu?s arteritis. Methods: This is a retrospective observational study of 28 patients who were diagnosed with Takayasu?s Arteritis and who presented to the department of Vascular Surgery, between January 2012 to January 2018. Their clinical presentation , angiographic findings, and outcome following intervention was analyzed. Results: 28 patients were analysed during study period. Among 28 patients, 25(89%) were female and 3(11%) were male. Average age of presentation was 29.34 years. Constitutional symptoms were reported in 13 patients(46.43%) and claudication in 11 patients(32%) .The commonest finding was hypertension in (57%) followed by absent pulses in 10 patients (42%). Major organ involvement was seen as cerebrovascular accident in 1 patient(7.14%) and cardiac findings included - chest pain 2(10.71%), aortic regurgitation 4(14.29%), mitral regurgitation or valve prolapse 2(7%) and pulmonary hypertension 2(7%) . According to the new angiographic classification,type I(32.14%) was encountered most frequently, followed by type III (25%), type IV (21.4%), type V (14%) and type IIb(7%) .The commonly involved vasculature was abdominal aorta(32%) , renal artery(25%) ,left subclavian (25%) followed by thoracic aorta(14%) and right subclavian (10%). Renal artery angioplasty was done in 5 patients and aneurysm repair was done in 1 patient with good outcome. Conclusion:-Takayasu?s Arteritis is a rare disease, with female predominance and varied clinical presentation. Angiography findings and clinical symptoms are integrated to decide management. Angiographic evaluation and percutaneous transluminal angioplasty with stenting is useful in selected cases; while majority of the patients are managed medically.