GG Polymorphism of Platelet ITGA2B Gene Increases the Magnitude of Interleukin-6 Release after Cardiopulmonary Bypass
Journal: Imaging Journal of Clinical and Medical Sciences (Vol.3, No. 1)Publication Date: 2016-12-30
Authors : Koray Ak Samet Ergun Hilal Altınoz Z Oya Uyguner; Sermin Tetik;
Page : 024-029
Keywords : ;
Abstract
Objective: Cardiopulmonary bypass (CPB) induces a systemic inflammatory response which is thought to be a significant cause of postoperative organ dysfunction and mortality. In this study we aimed to investigate the effect of ITGA2B (integrin alpha 2b, platelet glycoprotein IIb of IIb/IIIa complex) gene polymorphism on the magnitude of inflammatory response after CPB.
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