Management of Two-Wall Infra-Bony Defect with Platelet Rich Fibrin and Connective Tissue Graft Combination: A Case Report

Background: Regenerative procedures offer a limited potential toward achieving a complete periodontal regeneration and today, there is not any single material that can be considered as ‘gold standard' in infra bony defect treatment. Platelet-rich fibrin (PRF) is the second-generation platelet concentrate and represents a slow release system for growth factors. Use of PRF showed promising results in various periodontal surgical procedures.