Outcomes following total Laryngectomy for Squamous Cell Carcinoma at a Singapore Tertiary Referral Centre

Objectives: To evaluate the clinical outcomes and complications following total laryngectomy in a South-East Asian Population. Design: 10-year retrospective review of cases of total laryngectomy or laryngo-pharygectomy. Main outcome measures: 5-year overall survival (OS) and disease-free survival (DFS). Results: 61 patients of which 55 (90%) had laryngeal SCC while 6 (10%) had hypopharyngeal SCC. Overall edian survival was 85 months. 5-year OS and DFS for laryngeal SCC were 65% and 47% respectively while 5-year OS and DFS for hypopharyngeal SCC were both 33%. Most common cause of death was due to advanced cancer secondary to disease recurrence.