Amyloidosis in colon presenting with rectal bleeding in multipl myeloma: A Case Report

Multiple myeloma (MM) is a malignant proliferation of plasma cells that secrete monoclonal immunglobin (M protein). It accounts for 1% of all cancers and 10% of hematological malignancies. Mean age at diagnosis is 66 years. The most common fi ndings are bone pain, pathological fractures, anemia, bone marrow failure, Infections triggered by neutropenia and immunodefi ciency, and kidney failure and rarely can cause acute hypercalcaemia, symptomatic hyperviscosity, neuropathy, amyloidosis and coagulopathy. Amyloidosis is a rare disease characterized by nonspecifi c symptoms and signs. It can be seen anywhere in the gastrointestinal tract. In this case, a colonoscopy was performed on the patient who was directed to gastroenterology clinic with rectal bleeding and amyloidosis was detected in the biopsy from tumoral lesions seen in the colonoscopy.