Study of micro-albuminuria in diabetic nephropathy

The prevalence of diabetes mellitus is increasing worldwide. Recent studies showed that India has got large number of diabetic patients. Diabetic nephropathy (DN) develops in 30% to 40% of patients with type 1 diabetes mellitus and in 10% to 20% of patients with type 2 diabetes mellitus. Diabetic nephropathy is the leading cause of end-stage renal disease (ESRD) worldwide. An early sign of impending nephropathy is microalbuminuria. A total number of 90 samples were analyzed to study the microalbumin levels in 30 diabetic nephropathy patients, 30 diabetic patients without nephropathy and 30 healthy controls. The mean and standard deviation were calculated for all the parameters. The significance between the groups were determined using Student - test for Equality of means. The results show increase in mean concentration of microalbumin in diabetic nephropathy cases when compared to controls and was statistically highly significant (p< 0>