Spectrum of gallbladder diseases- a comparative study in North Vs South Indian population

Introduction: Cholecystectomy specimens are frequently received specimens. The number of cholecystectomy has increased more than 50% in the last decade, a vast majority performed annually for gallstone related diseases. Present study was done to study the morphological features of cholecystectomy specimens & to compare the spectrum of gallbladder diseases in both the populations in North Indian as well as South Indian populations. Materials and Methods: A total 800 cholecystectomy specimens (400 cases each from North India & South India) were studied at Kasturba Medical College, Mangalore and Postgraduate Institute of Medical Sciences & Medical Research and associated Dr. Ram Manohar Lohia Hospital, New Delhi. Results: Gender distribution (M:F) in North India was 1:4.88, whereas in South India it was 1:1.33. Chronic cholecystitis was significantly higher in North Indians (84%) as compared to South (66.75%). Gallbladder carcinoma was more common in North India (2%) as compared to South (1.25%). Dysplasia associated with cholecystitis was more common in North India (2.50%) as compared to South (1.75%). Associated cholesterolosis was significantly seen in North Indian study group (17.75%), whereas no case was seen in South.