RELATIONSHIP OF THE CONDITION OF THE MYOCARDIUM WITH INFRINGEMENTS THE CALCIUM AND PHOSPHORUS METABOLISM INPATIENTS WITH DIABETIC NEPHROPATHY
Journal: Ukrainian Journal of Nephrology and Dialysis (Vol.2, No. 54)Publication Date: 2017-06-22
Authors : I.I. Topchii; V.P. Denisenko; O.M. Kirienko; P.S. Semenovykh; Yu.S. Yakimenko; V.V. Mazii; O.M. Schenyavskaya;
Page : 27-32
Keywords : diabetic nephropathy; myocardium; phosphorus-calcium metabolism.;
Abstract
Objective: To establish the possible relationship between changes in cardiac hemodynamics and im-paired phosphate-calcium metabolism and content FGF 23. Patients and Methods: 260 people with diabetic nephropathy, 64 people with hypertension and 20 healthy individu-als were surveyed. Studied the state of the myocardium and cardiac hemodynamics, blood levels of calcium, phosphorus and FGF 23. Results and conclusions: between the state of myocardium, cardiac hemodynamics and content FGF23, phos-phorus and calcium are closely interrelated, which is likely mediated through specific receptor apparatus of myocardium and through immunoinflammatory mechanisms. However, the specific mechanisms of action system FGF23 / phosphorus-calcium exchange for anatomical and functional myocardial changes require further investigation.
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