ANTIMICROBIAL RESISTANCE IN PATHOGENS CAUSING URINARY TRACT INFECTIONS

There is an increase of the number of patients with urinary tract infections in Ukraine. The objective. To determine the spectrum of susceptibility to the antibiotics of major groups of pathogens of the uri-nary tract infections among the population of Chernivtsi region. Materials and methods. In order to conduct an accurate bacteriological study 2828 urine samples of patients of medical institutions in Chernivtsi region were examined during 2009 - 2013 aiming at verification of the diagnosis «urinary tract infections» (UTI). Results and discussion. The total amount of 801 strains of bacteria and fungi was extracted in etiologically signifi-cant quantities. The susceptibility of the extracted strains was identified concerning 24 antibiotics. It was revealed that thesusceptibility to antibiotics of the main group of pathogens of the urinary tract infections (except genus Proteus) depended on the age and sex of patients. Strains of bacteria that belong to major groups of pathogens of the urinary tract infec-tions (Enterobacteriaceae, Pseudomonas) are highly sensitive to carbapenems and aminoglycosides. The susceptibility to cephalosporins of the 3rd - 4th generations (to a greater extent in strains extracted from female patients), fluoroquinolones remains relatively high. Conclusion. The use of penicillins, cephalosporins of the first and second generations, tetracyclines, kanamycin and chloramphenicol without bacteriological urine analysis and determination of susceptibility to antibiotics is inappropriate.