Sero-prevalence of Hepatitis B and C virus and High Risk of Hepatotoxicity among TB/HIV Positive and HIV Negative Population in Western Cameroon

Background: Hepatitis and HIV are the most common co-infections in tuberculosis (TB) patients and may have an effect on the liver enzymes in these co-infected TB patients. This study aimed to determine the prevalence of Hepatitis B, C and HIV in patients infected with TB in Western Cameroon and assess the effects of co-infection on their liver function. Materials and Methods: All TB infected patients referred to the Tuberculosis Research centres, from November 2014 to July 2015, and who gave their consent were screened for Hepatitis B surface antigen (HBsAg) & Hepatitis C virus (VHC) antibodies using enzyme linked immunoabsorbent assay (ELISA). HIV infection was confi rmed using a combination of two rapid tests, namely, Combaids and Tridot. All HIV positive patients were on antiretroviral therapy during the study period. The data was entered and analysed using statistical Package for social sciences 21 (SPSS– 21), and the means and proportions were calculated.