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LONG QT SYNDROME. PART 1

Journal: Journal of the Grodno State Medical University (Vol.16, No. 4)

Publication Date:

Authors : ;

Page : 388-393

Keywords : long QT syndrome; torsade de pointes polymorphic ventricular tachycardia; drug-induced LQTS; syncope;

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Abstract

Long QT syndrome (LQTS) is a potentially life-threatening channelopathy, accompanied by a prolonged QT interval on a 12-channel ECG, syncopal conditions and a high risk of sudden cardiac death due to the development of torsade de pointes (TdP) polymorphic ventricular tachycardia. The primary goal in the management of patients with LQTS at the present stage is prevention of undiagnosed forms, its adequate treatment and prophylaxis, facilitated by the rapid development of molecular biology and genetics. The first part of the present review reflects the history of LQTS research and the latest achievements in studying its etiology, epidemiology, pathogenesis and clinical features.

Last modified: 2018-09-12 15:56:51