Does Acute Kidney Injury Alter Energy Metabolism of Septic Patients?

Background: The determination of resting energy expenditure (REE) in critically ill patients is essential to prevent hypo and hyper alimentation. Objectives: This study aims to describe the REE in septic patients with and without acute kidney injury (AKI) and compare by examining the REE estimated by Harris-Benedict equation (HB) with the REE measured by indirect calorimetry (IC). Methods: Prospective study was performed in septic patients older than 18 years, undergoing mechanical ventilation, with or without AKI defined by KDIGO criteria, and admitted to the Intensive Care Unit of University Hospital. The REE was estimated by HB equation and measured by IC within 72 hours after the diagnosis of sepsis and seven days after the initial measure.