Relationship between asthma and related factors of birth

BACKGROUND: Asthma is the most common chronic disease of childhood that causes disturbance in the physical, emotional, mental health, and different information has been mentioned on its risk factors, including factors associated with birth. Therefore, in this study, the relationship between children asthma and factors associated with birth was studied. METHODS: This case-control study was performed on 50 children with asthma as the case group and 150 children hospitalized without asthma as the control group (after matched for age and sex) in an age range of 4-14 years old. Information required on factors affecting asthma was recorded for both groups. Data analysis was performed using SPSS for Windows software. RESULTS: The results of this study showed that the majority of children in the case group were males born through cesarean operation (C-section). A significant difference was seen between two groups in terms of factors such as preterm [odds ratio (OR) = 3.27, confidence interval (CI) 95% = 1.57-6.81] and family history of asthma (OR = 8.50, CI 95% = 4.10-17.60). Regression model of relational variables with asthma show that the family history of asthma was most effective determinant on birth-related factors of asthma. CONCLUSION: The findings of this study showed that positive family history of the disease and premature-birth in infant correlates significantly and directly with asthma occurrence in children. Thus, it is recommended to make further follow-ups in providing prenatal care and early diagnosis of the disease.