Marine Sourced Glycosaminoglycans ‘GAGs’
Journal: Journal of Advanced Laboratory Research In Biology (Vol.5, No. 3)Publication Date: 2014-07-01
Authors : Nur Hanim Zainudin; K. N. S. Sirajudeen; Farid C. Ghazali;
Page : 46-53
Keywords : Marine; Sulfated Polysaccharides; GAG; Crown-of-Thorns (COT);
Abstract
Globally, there is an uprising interest for availability of tangible, novel, added value, sustainable commercial exploitable therapeutic compounds from naturally derived sources. The paper will highlight bioactive compounds of therapeutic potential from marine sources such as polysaccharides, especially glycosaminoglycans. It is now well documented, and this effort combined with a green technological approach in sustainable natural biodiversity will allow the development of a new generation of therapeutics. Outsourcing for a biocompatible, non-mutational bioactive compound such as GAG's in a worldwide research and industrial agenda. Hence, the thorough understanding on how the biosynthesis, structure and function of complex glycosaminoglycans will reveal the polysaccharides from the marine environment could provide a valid alternative to traditional polysaccharides such as glycosaminoglycans.
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