Assessment of Immunotoxic response in Albino Rats following Nickel Nitrate Treatment
Journal: Journal of Advanced Laboratory Research In Biology (Vol.5, No. 3)Publication Date: 2014-07-01
Authors : Prabhu N. Saxena; Reena Yadav;
Page : 83-85
Keywords : Nickel nitrate; Albino rats; IgG; DLC; Granulocytes;
Abstract
Nickel nitrate affects body physiology and immunology following its absorption through food, water, air. Predetermined doses of nickel nitrate (Ni(NO3)2] in acute (1 d) and subacute (7, 14, 21 ds) treatments revealed a significant increase in IgG concentration and lymphocyte number, whereas, neutrophils and eosinophils registered significant fall. These alterations indicated heavy metal stress in Immunological parameters that become targets.
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