The “Gastro” Dilemma on the Management of Gastroesophageal Junction Tumours: What Tumorsubsite should they belong to, and what Approach should be Preferred?

Gastroesophageal cancers (including oesophageal, gastric and gastroesophageal junction lesions) are worldwide a leading cause of deathbeing relatively rare but highly aggressive [1]. In the last decades the frequency of the distal stomach cancer decreased, while the incidence of cancer of the cardia and Gastro-Esophageal Junction (GEJ) has been rapidly rising [2,3]. The GEJ anatomically separates the lower oesophagus from the proximal part of the stomach, where the squamous epithelium of oesophagus changes into the columnar epithelium of gastric cardia