Diabetes Research and Treatment

Over the past few years, various international research centres have been involved in the study and identification of genes predisposing to Type 2 Diabetes Mellitus (T2DM). Using different strategies like candidate gene, linkage and genomewide association studies, a large number of variants have been identified in many genes which have highlighted the role of genetics in the development of T2DM. The number of known T2DM variants has risen to over 60 including confirmation of variants identified earlier by candidate gene and linkage studies. This has led to identification of genes and pathways involved in the development and progression of the disease and have significantly improved our knowledge of one of the most serious health problems in the world.