Diagnostic Value of the New Simplified Criteria for Diagnosis of Autoimmune Hepatitis in Tunisian Patients

Background and Aims: In 1999, the diagnostic criteria of Autoimmune Hepatitis (AIH) have been revised by an international panel. This revised scoring system had a high diagnostic accuracy but was limited by its complexity. Subsequently, a simplified score has been proposed recently to enhance clinical practicability. The goal of this study was to compare the performance parameters of the revised and the simplified scores in Tunisian patients satisfying conventional pretreatment criteria for the diagnosis of AIH and other chronic liver diseases. Methods: Diagnostic scores were calculated using the revised and simplified criteria in patients with AIH, viral, cholestatic and metabolic chronic liver disease. The sensitivity, specificity, and predictability of each scoring system for the pretreatment diagnosis of AIH were determined