The Migration Route of Langerhans Cell

Langerhans cells are one kind of Dendritic Cells (DCs) playing some roles in immune systems, the most essential role is presenting antigen's information to T cells. When foreign substances go into the skin, LCs capture these and migrate with their information to the draining lymph vessels. Finally, LCs present the antigen's peptide to T cells in the lymph nodes. The route of LCs migration could be two ways, not only via lymph vessels but also vein vessels. In this time, I present about migration of LCs.