Physical Exercise Intervention in Autoimmune Disease

Autoimmune diseases originate from the inappropriate responses, i.e. immune responses, originating from the body against agents and tissues that are under normal circumstances present in the body, i.e. autoimmunity. These conditions may be restricted to particular organs or involve particular tissues at different sites or regions. Several criteria are considered to determine the categorization of the disorder: (i) direct evidence arising from transfer of pathogenic antibody or pathogenic T cells, (ii) Indirect evidence derived from the observations of disorder in experimental animal models of autoimmune disease, and (iii) circumstantial evidence from clinical indications [1]. Treatments and interventions, typically, are designed to reduce the immune response. Autoimmune diseases include a huge variety of disorder conditions [2], not least of cardiovascular disease conditions, systemic lupus erythematosus and Multiple Sclerosis (MS).