KIDNEY HISTOPATHOLOGICAL OBSERVATIONS ON PLASMODIUM VINCKEIVINKEI INFECTION IN PROTEIN-MALNOURISHED MICE

Cellular and histopathological observations were made with light microscopy during the Plasmodium vinckeivinckeiinfection in protein-malnourished mice (fed on 2% casein diet and para-aminobenzoic acid deficient diet (PABA-DD). Some glomerula swelling and an increased thickness of the basement membrane is evident with ingested malarial pigments in the capillaries of glomerula. Tubular nephrosis which is characterized by degeneration of the proximal convoluted tubules with pyknotic nuclei which were reported for the first time. Haemoglobin casts were noticed inside the tubules.