WHEN THE TREATMENT OF A PATHOLOGY AGGRAVATES ANOTHER.TERBINAFINE AND PSORIASIS: TWO CASES REPORT

Terbinafine is an allylamine having an in vitro fungicidal effect on dermatophytes and fungistatic on Candida albicans. It is an agent widely used in dermatology but also in general medicine and other specialties. It is, however, responsible of side effects in 10.5% of patients, mainly gastrointestinal and cutaneous. These cutaneous manifestations occur in 2.7% of patients in the form of erythema, urticaria, eczema, pruritus or rarely of alopecia areata. Cases of erythema multiforme / toxic epidermal necrolysis and Stevens-Johnson syndrome have been reported. We report the cases of two patients who had psoriasis lesions after taking oral terbinafine.