INSILICO STRUCTURAL ANALYSIS AND DRUG DOCKING STUIDIES ON RIBULOSE -1, 5 BISPHOSPHATE CARBOXYLASE IN GRACILARIA EDULIS
Journal: International Journal of Advanced Research (Vol.6, No. 9)Publication Date: 2018-09-08
Authors : Shoba. K Hebsibah Elsie. B; Jayakumari. S. Sathya. R.;
Page : 159-165
Keywords : Seaweed Bioindicator Rubisco Calvin cycle NCBI Bioinformatics Protein Modeling Drug target.;
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Abstract
Seaweeds are used in many countries as a source of food, for industrial applications and as a fertilizer. The major utilization of these plants as food is in Asia, particularly Japan, Korea, and china, where seaweed cultivation has become a major industry. The present uses of seaweeds at present are as human foods, cosmetics, fertilizers, and for the extraction of industrial gums and chemicals. They have the potential to be used as a source of long and short ? chain substances may be extracted by fermentation and pyrolysis. The protein ribulose 1,5bisphosphate present in this algae. The enzyme is commonly referred to as rubisco. The limiting reaction within the Calvin Cycle is carried out by the enzyme Rubisco. The enzyme is located in the chloroplasts' stroma. The sequences of Rubisco retrieved from National Centre for Biotechnology Information in fasta format. Using BLAST p, the similarities of the target protein was searched. Modeled protein is evaluated through Rapper Server.
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