EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF CARICA PAPAYA AND FICUS BENGALENSIS LATEX ON THIOACETAMIDE INDUCED HEPATOTOXICITY IN RATS

Study was designed to evaluate the hepatoprotective activity of Carica Papaya Latex at the dose 400mg/k.g. and Ficus Bengalensis Latex at the dose 300mg/k.g. per oral induced by thioacetamide at the dose 100mg/k.g. S.C..Hepatoprotective activity was observed by using bio-chemical parameters such as Serum-Glutamate Pyruvate Transaminase and Serum-Glutamate Oxalate Transaminase (SGPT and SGOT), total protein, Bilirubin, Alkaline Phosphate (ALP). Carica Papaya and Ficus Bengalensis Latex produced significant hepatoprotective effect by decreasing the activity of serum enzyme like SGPT, SGOT, Bilirubin, ALP, and elevated total protein level. Both plants latex were found completely prevented the toxic effect of thioacetamide on above serum parameters.