The Enterobacteriaceae Isolated from Urinary Tract Infections in Kerbala City

Objective: The goal of this study to determine the most common microorganism that causes urinary tract infection (UTI) in Kerbala city/ Iraq, and study of susceptibility of this causative agents against some antibiotics which used as treatments. Methods: Sixty specimens were collected from urinary tract infections in Kerbala city/ Iraq from September to December 2016. The bacterial isolates were identified tested for antibiotics sensitivity test. Resistance breakpoints used were those published by Clinical and Laboratory Standards Institute (CLSI), including: Nalidxic Acid (resistance ≥ 13 mm), Trimethoprim (resistance ≥ 10 mm), Norfoxacin (resistance ≥ 12mm), Ciprofloxacin (resistance≥15mm)and Trimethoprim/sulfamethoxazole(resistance≥10mm). Results: The most common organisms of UTI infection were Escherichia coli (48%), Citrobacter spp (22%), Proteus spp(12%), Klebsiella spp(8%), Pseudomonas spp(6%), Moragenella spp(2%) and Providencia spp(2%). Among all 50 isolates , 48% were resistance to Nalidxic Acid , 40% to Trimethoprim and 28% to Norfloxacinas. For the 24 Escherichia coli isolates, resistance rate were: Nalidxic Acid (50.0%) ,Trimethoprim (37.5 %), Norfloxacin (33.33%), Ciprofloxacin (16.67%) and Sulphamethoxaole/ Trimethoprim (58.33% ). Conclusion: From the results carried out in this study, it's concluded that E.coli isolates responsible for UTI infections and the higher rates of antibiotics resistance to Sulphamethoxaole/ Trimethoprim.