Osteogenesis Imperfecta a Case Report in Owerri, Nigeria

A week old male infant presented with severe tenderness all over the body with associated continuous crying. There was bowing of both limbs. A total body radiograph revealed multiple healed and healing fractures in the long bones and ribs. The long bones were short, broad and bowing with thinning of the cortex. The spine shows compressed, flattened and irregular vertebral bodies. Some infants� deaths has been recorded in the family. Osteogenesis imperfecta is a rare disorder of connective tissue which is characterized by skeletal deformity, bone fragility, fractures, ligament laxity, hearing loss, blue sclera, dental abnormality and thin skin. All those features will not manifest in one case; they are therefore group into four types and subtypes. This case is more of Type 2 and Type 2A Osteogenesis imperfecta.