The Effect of Nigella Sativa Lin. Black Seeds/Kalonji (Family Ranunculaceae) On Hyperglycemia, Dislipidemia and Serum Uric Acid in Human Diabetics

Objective: The objective of this study was to investigate the effect of Nigella sativa Lin. (Nigella sativa L.) on Serum Glucose, Cholesterol, Triglycerides and Uric Acid concentration (mg/dl) in patients suffering from Diabetes mellitus type 2 compared to normal) human beings. Methods: Nigella sativa was selected to estimate its effect on Serum Glucose, Cholesterol, Triglycerides and Uric Acid in diabetics and normal (control) human beings. Previous workers, fed 2gm/day Nigella sativa L. as crushed seed with meals. The present study continued for 42 days and serum samples were collected on Day 01, Day 28 and day 42. The above parameters were estimated by using enzymatic kits through spectrophotometry. Results: The results revealed significant decrease(P<0.05) in Serum Glucose, Cholesterol, Triglycerides and Uric Acid in diabetics on Day 28 and the decrease further increased on Day 42 as compared to Day 01, or with control individuals. The Nigella sativa Lin. did not show any significant effect on any of the above parameters in normal individuals. Conclusion: It can be concluded that Nigella sativa L. can be safely substituted allopathic treatment of diabetics to manage the disease with beneficial effect on its dislipidemic and uricemic complications.