STATUS OF TNF-α AND INSULIN IN OBESE AND DIABETIC OBESE SUBJECTS OF WESTERN LUCKNOW

Obesity has become a matter of quality to health care administrators. The busy lifestyle of people made them prefer fast food instead of taking healthy food. But the people are not aware that fast food habit converts to the disease like obesity, type 2 diabetes mellitus (T2DM), dyslipoproteinemia etc. This case control study had been carried out in department of Physiology in collaboration of Department of Biochemistry and Medicine, Era's Lucknow Medical College & Hospital, Lucknow to explore status blood sugar fasting (BSF), tumor necrosis factor-α (TNF- α), Insulin by standard spectrophotopmetric kit methods, blood pressure (BP) as well as anthropometric measurements with the help of suitable instruments and equipments in Control group, Obese group and Obese with type 2 diabetic group. Values of all above parameters were found increased in obese group with respect to control group and values of all these parameters were found increase in obese with type 2 Diabetes mellitus group with respect to obese group. Thus it is clear that obesity is risk factor for T2DM, Dyslipoproteinemia and coronary artery disease (CAD).