CLINICAL FEATURES OF PYO-DERMIA COURSE

Cutaneous bacterial infection is divided into primary and secondary type. Primary infections have a characteristic morphology and course, caused by a single organism, and arise in normal skin. Primary infections are most frequently incited by coagulase positive Staphylococci or beta-haemolytic streptococci. They are also the most common invaders in secondary infection. Pyodermia is one of the most common clinical conditions encountered in dermatological practice. Primary pyodermias are impetigo, follicultis, furuncle, carbuncle, ecthyma, erthyrasma, and sycosis barbae. Secondary pyodermias constitute tropic ulcer, infected pemphigus, infected contact dermatitis, infected scabies, and various other dermatoses infected with organisms. Various factors like poverty, malnutrition, overcrowd-ing, and poor hygiene have been stated to be responsible for its higher incidence in the lower socio-economic class. Climatic conditions also play a major role. Changing trends are being noted in the etiological aspects of primary pyodermia, and the problem of emergence of drug resistance strains is an even increasing one. Most common organism usually isolated in pyoderma is Staphyloccus aureus, which may be either methicilllin-sensitive (MSSA) or methicilllin-resistant (MRSA). MRSA is an important health care associated pathogen. Many of these isolates are becoming multidrug resistant. All β-lactams including carbapenams and high-end cephalosporins, piperacillin, tazo-bactum etc. are ineffective against MRSA. Knowledge of prevalence of MRSA and their current anti-microbial profile becomes necessary in the selection of appropriate empirical treatment of these infections. Pyodermia has become a significant cause of skin infections. When the natural defense system of the body breaks down due to trauma, after invasive procedures, or chemotherapy, the normally benign bacteria can cause infection. The aim of our study was evaluation of clinical features of pyodermia course. One hundred and eleven patients with pyodermia were observed in this study. We used all clinical and laboratory tests for recognition of pyodermia. Among all observed patients were 69 males and 42 females, aged 16-64 years. More often pyodermia was diagnosed in physical profession persons. In 67. 6% patients the comorbid conditions (inner organs pathology) were diagnosed. Among all types pyodermias the most often were superficial folliculitis. Acute and subacute course of this disease was established in 25.1% cases, chronic and recidives – in 73.9% cases. Conclusions. The clinical features of pyodermia course include high prevalence among males, frequent involving into pathological process different anatomical zones, high level of its chronization, inner organs co-morbidity.