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SERUM INTERLEUKIN 13 (IL-13) LEVELS IN IRAQI CHILDREN WITH NEPHROTIC SYNDROME

Journal: International Journal of Advanced Research (Vol.6, No. 10)

Publication Date:

Authors : ; ;

Page : 385-388

Keywords : Interleukin Nephrotic syndrome Steroid sensitive Steroid resistance.;

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Abstract

The aim of this study is to compare the levels of IL-13 in children with nephrotic syndrome and healthy control children. Fifty children with NS were divided into four groups: 14 steroid sensitive infrequent relapse (SSIFR), 12 steroid sensitive frequent relapse (SSFR), 9 steroid resistance (SR) and 15 newly diagnosis (ND) compared to twenty-five unrelated healthy children. The serum IL-13 levels for NS patients and healthy control children were measured by R&D quantitative ELISA kit. The results of mean IL-13 level in healthy children serum (205.18 ? 2.61 pg/ml) was significantly lower than children with NS (335.50 ? 40.68 pg/ml). we showed serum IL-13 was increased significantly (P= 0.0271) in children with NS in compared with healthy control children, this raised in IL-13 levels could have a role in nephrotic syndrome pathogenesis.

Last modified: 2018-11-10 16:54:06