ENDOMETRIAL TUBERCULOSIS: AN IMPORTANT CAUSE OF INFERTILITY IN A DEVELOPING COUNTRY

Background :Endometrial tuberculosis , important cause of secondary amenorrhoea and infertility where tuberculosis is endemic.Materials and methods : Random sampling of patients failing to conceive for a year included in study conducted in tertiary care hospital, where congenital abnormalities and problems regarding husband excluded.Tests conducted were routine blood examination with hormone assays, ultrasonography, hysterosalpingography and endometrial tissue biopsy. Endometrial tissue culture done in case of infections with PCR.Results : Among 100 female subjects;28 were hypothyroid,16 were hyperprolactinemic. Endometrial biopsy showed 47 cases of anovulation , 32 showed luteal phase defects and 5 showed features of endometrial tuberculosis confirmed by staining by Z-N method, culture and PCR study. Conclusion : Apart from hormonal imbalance; infections specifically tuberculosis can be an important cause of infertility and must be taken care of.