PATHOMORPHOLOGICAL STUDIES IN NEWBORN PIGS INDUCED BY INFECTIONWITH VACCINAL STRAIN МК 35GE- AND FIELD ISOLATES MOGILA AND ST. ZAGORA OF SUID HERPESVIRUS 1. PART I. NERVOUS SYSTEM

The purpose of the present study was to perform a comparative morphological analysis of the changes in the central nervous system of new-born pigs prior to colostrum intake. The infection was artificially created by application of a vaccine strain MK 35gE- and two strains, isolated from intrauterine infection cases – Mogila and Stara Zagora II. A restriction profile of the viral strains was made. No neurological signs or 100% mortality were registered in the pigs that were infected with the strains St. Zagora II and MK 35gE-. Pathohistological changes caused by these two strains of the virus in animals CNS were similar and were characterized primarily by reproductive problems. The pathological changes induced by Mogila strain were obvious by presence of alteration, exudation, and proliferation (less pronounced) in the brain.