ISOLATED ADULT HYPOGANGLIONOSIS OF THE COLON - A CASE REPORT

We report a 42 year old male, a case of megacolon from adult hypoganglionosis. The patient suffered from intractable constipation since childhood and presented with abdominal distension. He also had surgery for sigmoid volvulus in the past. Barium enema and computed tomography revealed markedly dilated large bowel with a transition zone. A full thickness biopsy of the rectum showed a reduction in ganglion cells, thereby giving a diagnosis of adult hypoganglionosis of the colon or pseudo-Hirschsprung's disease. Keyword