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β-CYCLODEXTRIN MODIFIED GRAPHENE/TYROSINASE BASED BIOSENSOR FOR DOPAMINE DETERMINATION
Journal: Analele Universitatii din Oradea.Fascicula Chimie (Vol.23, No. 1)Publication Date: 2016-12-15
Authors : Mihaela TERTIȘ Cecilia CRISTEA Serge COSNIER Robert SĂNDULESCU;
Page : 15-22
Keywords : biosensor; reduced graphene oxide; β-cyclodextrin; tyrosinase; real samples;
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Abstract
A cyclodextrin-modified graphene composite was obtained by noncovalent functionalization of graphene with β-cyclodextrin leading to an effective aqueous dispersion of the exfoliated graphene sheets. This nanocomposite was characterized by using spectral, microscopic and electrochemical techniques. The reduced graphene oxide modified with β-cyclodextrin was used in combination with tyrosinase entrapped in polyethylenimine film for the elaboration of a biosensor which was successfully applied for dopamine determination in biological samples by amperometry
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Last modified: 2018-12-10 19:34:03